UPTON, NY—Scientists studying a COVID-19 coronavirus enzyme at temperatures ranging from frosty to human-body warm discovered subtle structural shifts that offer clues about how the enzyme works. The ...

A research team maps the key tasks that define modern enzyme engineering—function annotation, structure modeling, and property prediction—and explain how AI methods now accelerate each step, from ...

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

Biochemists have succeeded in resurrecting the ancestral genes of five detoxifying enzymes which are present in all tetrapods to show how their divergence in function has occurred. Our body produces ...

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. Researchers said the AI tool, ...

At the University of Tokyo, Prof. Osamu Nureki's group works on identifying the structure and function of the proteins involved in genome editing. In a recent study by the team, they discovered the 3D ...

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

For the first time, the structure of a DNA enzyme complex implicated in infertility and cancer has been obtained using cryo-electron microscopy (cryo-EM). A collaboration of researchers, led by ...

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...

Current demand for plastics and chemical raw materials is met through large-scale production of ethylene from fossil fuels. This makes it necessary to search for new, renewable processes. Using ...